General Cell Based Assays
Eurofins Discoverx PathHunter NPY2R Bioassay Kit, 2-Plate. (93-0212Y2-00065)
The PathHunter NPY2R Bioassay kit provides an easy-to-use cell based assay to measure drug potency and detect neutralizing antibodies. This bioassay assesses ligand (e.g. peptide YY) based activation of NPY2R GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged NPY2R and EA-tagged β-Arrestin-2. Activation of NPY2R stimulates the recruitment of β-Arrestin-2 and produces EFC signal. Bioassay kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, control agonist, detection reagent, and assay plates. For detailed product information, User manual and COA, visit www.discoverx.com/bioassay.
Eurofins Discoverx PathHunter eXpress P2RY8 CHO-K1 β-Arrestin Orphan GPCR Assay, 10-Plate Kit. (93-0635E2CP1L)
The PathHunter P2RY8 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. UTP) based activation of P2RY8 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged P2RY8 and EA-tagged β-Arrestin-2. Activation of P2RY8 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress rCRTH2 CHO-K1 β-Arrestin GPCR Assay, 2-Plate Kit. (93-0580E2RCP2M)
The PathHunter rCRTH2 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. prostaglandin D2) based activation of rCRTH2 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged rCRTH2 and EA-tagged β-Arrestin-2. Activation of rCRTH2 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. Please note that this product expresses the Rat version of this protein. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx AssayComplete Cell Plating 36 Reagent, 100. (93-0563R36A)
AssayComplete Cell Plating 36 Reagent is an optimized cell plating reagent for use in plating of Eurofins DiscoverX cell lines for assays. This reagent was optimized for maximal cell health and ligand responsiveness during assays while eliminating hormones and growth components which may lead to increased basal activity. This product is provided as a bottle of 100 mL. Please refer to cell line specific datasheet to determine the recommended cell plating reagent. For detailed product information, User manual and datasheet, visit www.discoverx.com/reagents.
Eurofins Discoverx PathHunter eXpress GPR6 U2OS β-Arrestin Orphan GPCR Assay, 10-Plate Kit. (93-0634E3CP1L)
The PathHunter GPR6 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand based activation of GPR6 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged GPR6 and EA-tagged β-Arrestin-2. Activation of GPR6 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. This is an orphan receptor without a known ligand. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress mPTAFR CHO-K1 β-Arrestin GPCR Assay, 2-Plate Kit. (93-0614E2MCP2M)
The PathHunter mPTAFR eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. PAF) based activation of mPTAFR GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged mPTAFR and EA-tagged β-Arrestin-2. Activation of mPTAFR stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. Please note that this product expresses the Mouse version of this protein. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx AssayComplete Cell Plating 38 Reagent, 500. (93-0563R38B)
AssayComplete Cell Plating 38 Reagent is an optimized cell plating reagent for use in plating of Eurofins DiscoverX cell lines for assays. This reagent was optimized for maximal cell health and ligand responsiveness during assays while eliminating hormones and growth components which may lead to increased basal activity. This product is provided as a bottle of 500 mL. Please refer to cell line specific datasheet to determine the recommended cell plating reagent. For detailed product information, User manual and datasheet, visit www.discoverx.com/reagents.
Abcam Glycogen Assay Kit
Glycogen Assay Kit
The product is subject to the following: Abcam Restricted Use Statement
Abcam Cell Cycle Analysis Kit
Cell Cycle Analysis Kit
The product is subject to the following: Abcam Restricted Use Statement
Abcam Lysosomal Intracellular Activity Assay Kit
Lysosomal Intracellular Activity Assay Kit
The product is subject to the following: Abcam Restricted Use Statement
Abcam Asparaginase Activity Assay Kit
Asparaginase Activity Assay Kit
The product is subject to the following: Abcam Restricted Use Statement
Abcam Glyceraldehyde 3 Phosphate Dehydrogenase Activity Assay Kit (Colorimetric)
Glyceraldehyde 3 Phosphate Dehydrogenase Activity Assay Kit (Colorimetric)
The product is subject to the following: Abcam Restricted Use Statement
Abcam Glucose Uptake Assay Kit (Colorimetric)
Glucose Uptake Assay Kit (Colorimetric)
The product is subject to the following: Abcam Restricted Use Statement
Eurofins Discoverx PathHunter eXpress ErbB4/ErbB4 Dimerization Assay, 10pl Kit. (93-0961E3CP5L)
The PathHunter ErbB4/ErbB4 Dimerization eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting receptor-receptor interaction. This kit assesses ligand (e.g. neuregulin-1 Beta 2) induced dimerization of ErbB4/ErbB4 receptors. This product uses EFC technology. The cell line included overexpresses ErbB4 target protein fused to PK alongside ErbB4 target protein fused to EA. Upon ligand-induced dimerization of ErbB4/ErbB4, detectable EFC signal is produced. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.